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Sesbania grandiflora (L.) Poir.

Summary
It is commonly known as Agasti and belongs to the Fabaceae family. Flowers and fresh leaves are cooked and eaten as vegetable. The young leaves and the tender pods of this plant are used to supplement meals and as vegetables. Sesbagrandiflorain A, B and C, Saponin, Catechol, Quercetin, Oleanolic acid are some of the bioactive compounds reported from this plant. Methanolic extract of S. grandiflora possesses immunomodulatory and anti-cancer activity. Methanolic extract derived from S. grandiflora flowers not only potentiates nonspecific immune response, but also improves humoral as well as cell-mediated immunity effectively.

Mode of Consumption : Fried and cooked
Plant Details Agro-climatic Zone Vernacular Names Pictures
Scientific Name: Sesbania grandiflora (L.) Poir.
Family: Fabaceae Lindl.
Class: Magnoliopsida
Order: Fabales
Genus: Sesbania Adans.
Fruiting Season: September to December (Flower), April-July (Fruit)
Parts: Flower, Fresh leaves
  • Andaman & Nicobar Island Region
  • The Eastern Coastal Region
  • The North-Eastern Hill Region
  • The Middle Ganga Plain Region
  • The Western Rajasthan Region
  • The Upper Ganga Plain Region
  • The Western Coastal Region
  • The Gujarat Region
  • The Satluj-Yamuna Plain Region
  • North-Western Mountain Region
  • The South-Eastern Plateau Region
  • The Deccan Interior Region & The Western Coastal Region
  • The Aravali-Malwa Upland
  • The Maharashtra Plateau Region & The Western Coastal Region
  • The South-Eastern Plateau Region & The Eastern Coastal Region
  • The Western Rajasthan Region & The Aravali-Malwa Upland
  • The Deccan Interior Region & The Eastern Coastal Region
  • The Deccan Interior Region
  • The Upper Ganga Plain Region & The Middle Ganga Plain Region
  • The Lower Ganga Plain Region
 Assam : Bokphul
Bihar : Hathya,Agasti, Gaach-munga
Delhi : Hathya,Agasti, Gaach-munga
Gujarat : Agathio
Haryana : Hathya,Agasti, Gaach-munga
Jharkhand : Hathya,Agasti, Gaach-munga
Karnataka : Agase, Agasi
Kerala : Akatti
Madhya Pradesh : Hathya,Agasti, Gaach-munga
Maharashtra : Shevari, Hatga
Manipur : Houwaimal
Rajasthan : Hathya,Agasti, Gaach-munga
Tamil Nadu : Muni,Sevvagatti
Telangana : Avisaku
Uttar Pradesh : Hathya,Agasti, Gaach-munga
Uttarakhand : Hathya,Agasti, Gaach-munga
West Bengal : Agusta, Bagphal, Bak, Bake

Flowers
Compound/Extract Activity Mode of Action Marker/References
Methanolic extractImmunomodulatoryMethanolic extract derived from S. grandiflora flowers not only potentiates nonspecific immune response, but also improves humoral as well as cell-mediated immunity effectively.B-cells and T-cells[3]
Methanolic extractImmunomodulatoryMethanolic extracts of Sesbania grandiflora and Cocculus hirsutus both significantly increase or activate the secretion of immunoglobins such as IgM and IgG. Combining Sesbania grandiflora and Cocculus hirsutus in the ratio of 1:1 of 100-400mg/kg gives good immunomudulatory activity compared with 1:2 and 2:1 ratios.IgM and IgG[4]
Methanol extractAnticancerThe methanol extract of flowers of Sesbania grandiflora showed potential anticancer activity against Ehrich ascites carcinoma bearing Swiss albino mice. [5]
Ethanolic extractHepatoprotectiveOral administration of ethanolic extract of Agathi leaves produced significant hepatoprotection against erythromycin estolate induced hepatotoxicity in rats. [5]
Flower extractAnticancerAgathi flower extract significantly inhibited the growth of HeLa cancer cell line. [5]
Protein fraction from flowerAnticancer, ChemopreventiveA novel protein fraction from Agathi flower shows potential anticancer and chemopreventive efficacy, against Daltons lymphoma ascites (DLA) and colon cancer cells (SW-480). [5]
Ethanolic extractAnticancerEthanol extract from leaves and flowers also exhibited anticancer activity in Ehrlich ascites carcinoma induced model in mice. [5]
Methanol extractAnti-inflammatoryThe methanolic extract of Agathi registered profound anti-inflammatory activity against cotton pellet induced granuloma in the experimental rats. [5]
DecoctionAntidiabeticAmong several immunomodulatory agents tested, interleukin 10 (IL-10) was assessed as a cytokine that could be used in the treatment of diabetes.Therefore, searching for herbal remedies capable of accelerating IL-10 production could be a rational strategy in the immunomodulatory therapy of diabetes treatment. S. grandiflora seed decoction (2.5 g/kg BW) could lower blood glucose of streptozotocin (STZ) induced diabetic mice. Relative amounts of interleukin-10 were increased significantly, indicating the role of IL-10 in maintaining blood glucose homeostasis.IL-10[6]
Major Class Metabolites (Content of bioactives: mg/100g Fresh Weight)
2-(3,4-dihydroxy-2-methoxyphenyl)-4-hydroxy-6-methoxybenzofuran-3-carbaldehyde: , 2-(4-hydroxy-2-methoxyphenyl)-5,6 dimethoxybenzofuran-3-carboxaldehyde: [2]
2-arylbenzofuranSesbagrandiflorain A: , Sesbagrandiflorain B: , Sesbagrandiflorain C: [2]
FlavonoidQuercetin: [1]
Flavonol glycosideKaempferol-3-routineoside: [1]
Glycosidic compoundSaponin: [1]
PhenolCatechol: [1]
TriterpenoidOleanolic acid: [1]
Effect Observation DOI
Disease Formulation Reference Author TKDL
Internal abscess, Abdominal lump, Obesity, HeadacheVarunadegan Sharangadhara SamhitaTranslated by Smt. Shailaja SrivastavaAyurveda
AbscessVarunadiganakwathampakeSharangadhara SamhitaTranslated by Smt. Shailaja SrivastavaAyurveda
Fever with diarrhoea and vomitingMaantha Kazichalku MarunthuYakkopu VaithiyamYakkopu vaithiyam. Ed: Kuppusamy Naidu.Pub: Ramasamy kon (1967)Siddha
Information from Wealth of India Reference
  • Tender leaves, pods and flowers are eaten as vegetable
  • The juice of leaves and flowers is used in nasal catarrh and headache.
  • A poultice made from the leaf juice is applied to bruises.
  • Leaves are chewed to disinfect mouth.
  • Juice of the flowers is put in the eyes to cure dimness of vision.
 CSIR(1972).The Wealth of India, Raw materials,Vol.-IX ,P.295-298, New Delhi, India
4.2, 4.2.1, 4.2.1.1, 4.2.1.3, 4.2.2.8, 4.2, 4.2.1, 4.2.1.1, 4.2.1.3, 4.2.2.8
    CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
    CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India