Euryale ferox Salisb.
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It is commonly known as Makhana and belongs to the Nymphaeaceae family. Leaf petiole and tender fruits are consumed as vegetable. 5,7,4-trihydroxyflavanone, Buddlenol E and 5,7-dihydroxy2-(3,4,5-trihydroxyphenyl)-chroman-4-one are the phenolic compounds present as its bioactive markers. Ethyl acetate fraction of E. ferox in LPS stimulated RAW 264.7 inhibited the production of NO, PGE2 and reduced the pro-inflammatory cytokines TNFα, IL-1β and IL-6 . Mode of Consumption : Cooked, boiled, seeds roasted |
| Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
| Scientific Name: Euryale ferox Salisb. Family: Nymphaeaceae Salisb. Class: Magnoliopsida Order: Nymphaeales Genus: Euryale Salisb. Fruiting Season: June to October Parts: Leaf petiole, Tender fruits |
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Andhra Pradesh : Mellunipadmanu Assam : Makhana, Makhanda, Makhna, Nikharu, Nikori, Nikori utpal Bihar : Makhana Delhi : Makhana Haryana : Makhana Jammu & Kashmir : Makhana Jharkhand : Makhana Madhya Pradesh : Makhana Manipur : Thangjing Odisha : Kanta padma Rajasthan : Makhana Tamil Nadu : Karuntamarai, Mallani-padman Telangana : Mellunipadmanu, Makhana Uttar Pradesh : Makhana Uttarakhand : Makhana West Bengal : Makhana |
![]() Plant ![]() Roasted seeds |
| Compound/Extract | Activity | Mode of Action | Marker/References |
| Ethyl acetate fraction | Anti-inflammatory | Ethyl acetate fraction inhibited the production of NO, PGE2 and reduced the pro-inflammatory cytokines TNF-α, IL-1β and IL-6 in LPS stimulated RAW 264.7. | NO, PGE2, TNF-α, IL-1β, and IL-6[1] |
| Major Class | Metabolites (Content of bioactives: mg/100g Fresh Weight) |
| Carboxylic Acid | Gallic acid : [2] |
| Organosulphur compound | Alliin: [2] |
| Phenolic compound | 5,7,4-trihydroxyflavanone: , 5,7-dihydroxy2-(3,4,5-trihydroxyphenyl)-chrom an-4-one: , Buddlenol E: [2] |
| Phenols | Resveratrol: [2] |
| Effect | Observation | DOI |
| Disease | Formulation | Reference | Author | TKDL |
| Retentive and Aphrodisiac | Jawarish -e-muqawwi-e-bah | Quaraabaadeen Najm-al-Ghani | Mohd. Nazmul Ghani Khan | Unani |
| Spermatorrhoea | Safoof Jiryaan | Quaraabaadeen Najm-al-Ghani | Mohd. Nazmul Ghani Khan | Unani |
| Semen Inspissant and Retentive | Safoof Mughalliz | Quaraabaadeen Najm-al-Ghani | Mohd. Nazmul Ghani Khan | Unani |
| Information from Wealth of India | Reference |
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CSIR(1952).The Wealth of India, Raw materials,Vol.-III ,P.232, New Delhi, India |
| 4.2, 04.2.1, 04.2.1.1, 04.2.1.3, 04.2.2.5, 04.2.2.6, 04.2.2.8 |
| CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |