Amaranthus hybridus L.
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It is commonly known as Chua and belongs to the Amaranthaceae family. Both leaves and tender shoots are consumed as vegetable. Ascorbic acid, Riboflavin, Tocopherol, β-carotene, 2-caffeoylisocitric acid are the bioactive compounds found in it. Caffeic acid derivatives (CADs) exhibited anti-inflamamtory activity in LPS-challenged RAW 264.7 cells. CADs significantly lowered mRNA and protein levels of iNOS, TNF-α, and IL-6 in LPS-challenged RAW 264.7 cells. Mode of Consumption : Sauteed, fried and boiled |
| Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
| Scientific Name: Amaranthus hybridus L. Family: Amaranthaceae Juss. Class: Magnoliopsida Order: Lamiales Genus: Amaranthus L. Fruiting Season: February to April Parts: Leaves & Tender shoot |
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Andhra Pradesh : Dantukura Bihar : Chua, Chaulai Delhi : Chua, Chaulai Haryana : Chua, Chaulai Jharkhand : Chua, Chaulai Karnataka : Dantusoppu Madhya Pradesh : Chua, Chaulai Maharashtra : Rajgira Rajasthan : Chua, Chaulai Tamil Nadu : Thandukeerai, Punjikkeerai Telangana : Dantukura Uttar Pradesh : Chua, Chaulai Uttarakhand : Chua, Chaulai |
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| Compound/Extract | Activity | Mode of Action | Marker/References |
| 2-Caffeoylisocitric Acid | Anti-inflammatory | Treatment of LPS-challenged RAW 264.7 cells with 10 µM of CADs counteracted the LPS effects and led to significantly lower mRNA and protein levels of iNOS, TNF-α, and IL-6, by directly decreasing the nuclear translocation of the NF-κB/p65. | iNOS, TNF-α, IL-6, and NF-κB[1] |
| Aqueous extract | Anticacer | Aqueous extract pretreatment decreased the induction on micronucleated polychromatic erythrocytes (mPCEs) by sodium arsenite to about 1.1 folds in rats. | [2] |
| Major Class | Metabolites (Content of bioactives: mg/100g Fresh Weight) |
| Carotenoid | β- Carotene: [2] |
| Vitamin | Ascorbic acid: , Riboflavin: , Tocopherol: [2] |
| Effect | Observation | DOI |
| Disease | Formulation | Reference | Author | TKDL |
| Information from Wealth of India | Reference |
| 4.2, 04.2.1, 04.2.1.1, 04.2.1.3, 04.2.2.8 |
| CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |