Allium sativum L.
Garlic is a root vegetable belonging to the family Amaryllidaceae. Garlics are rich in organic sulphur compounds (Allicin, allin, ajoene and diallyl disulphide). Garlic enhances immunity by increasing the proliferation of natural killer cells and T cells and shows anti-cancerous activity by increasing glutathione, nitric oxide and INF-α cytokine levels in the body. Mode of Consumption : Fresh, fried, boiled and pickled |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Allium sativum L. Family: Amaryllidaceae J.St.-Hil. Class: Magnoliopsida Order: Asparagales Genus: Allium L. Fruiting Season: All round the year Parts: Bulb & Leaf |
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Andhra Pradesh : Vellulli Assam : Nohoru Bihar : Lehsun Himachal Pradesh : Lehsun Karnataka : Belluli Kerala : Vellutulli Punjab : Lehsun Tamil Nadu : Pondu Uttar Pradesh : Lehsun Uttarakhand : Lehsun West Bengal : Rosun |
![]() Bulb |
Compound/Extract | Activity | Mode of Action | Marker/References |
Garlic extract | Immunomodulatory | Encapsulated garlic extract helps in increasing proliferation and activity of NK cells and γδ-T cells as well as increases lymphocyte GSH concentration. | GSH, NK cells and γδ-T cells[8] |
Fresh bulb | Anticancer | Fresh bulb increases in Nitric oxide (NO) synthesis and increased levels of INF-α cytokine and its activity. | NO and IFN-α [9] |
Aqueous Garlic extract | Anticancer | Aqueous garlic extract contains S-allylmercaptocysteine which helps in diminishing human prostate cancer cells, rescue of GSH deficits, alteration of prostate biomarker expression and testosterone utilization and restoration of E-cadherin expression. | GSH and E-cadherin[10] |
Major Class | Metabolites (Content of bioactives: mg/100g Fresh Weight) |
Flavonoid | Quercetin: 0.9-1.98[6] |
Organosulphur compounds | Allicin: 91.08-336.96 mg/100g, Alliin: 598-1047.6 mg/100g, Diallyl disulfide: 29 mg/100g, Z-Ajoene: 16.92 mg/100g[1] |
Effect | Observation | DOI |
In vitro studies | Significant growth of Lactobacillus acidophilous | DOI: 10.14202/vetworld.2019.2046-2051 |
Human clinical studies | Significant increase in Bifidobacterium and Faecalibacterium strains | DOI: 10.3389/fnut.2022.1007506 |
Disease | Formulation | Reference | Author | TKDL |
Ulcer / Wound Healing(Pun), Gonorrhoea (Seezh Megam,Vellai noi,Mega noi), Oedema / Inflammation(Veekkam) | Merrugulli Thylam | Therayar Thailavarukka Churukkam | Therayar, Edited by Subramanya Pandithar, Published by Devaraja Nayakar, Chennai (Edn. 1958) | Siddha |
Flatus of piles(Moola vaayu), Distension of abdomen(Vayiru Porumal) | Vellulli Thayir | Agathiyar vaithya vallathi 600 | Agasthiyar, Edited by R.C.Mohan, Published byThamarai Noolagam, Chennai (Edn.1st, April 2001) | Siddha |
Flatulence(Nafkh-e-Shikam), Ptyriasis Nigra(Bahaq-e-Aswad), Alopecia (Daa-al-Sa'lab), Chronic Abscess(Dubaila), Ring worm (Qoobaa), Scabies, Itch(Jarab-wa-Hikka), Malignant Ulcers(Qurooh-e-Khabeesah), Sciatica (Irqun Nasaa),Headache (Suda'), Toothache(Waja'-ul- Asnaan), Asthenopia, Amblyopia(Zo'f-e-basar), Cough / Bronchitis(Sua'al/Surfah), Insect bite(Lasa't-al-Hasharaat), Rabies (A'zzat-ul-Kalbil mukallab), | Soom-[lahsan] | Al-Qaanoon-fil Tibb, Vol. II | Abu Ali Ibn-e-Sina, Institute of History of Medicine and Medical Research, Jamia Hamdard, New Delhi-62, 1987 | Unani |
Alopecia (Daa-al-Sa'lab), Alopecia Furfuracea(Daa-al-Hayyah) | Tila-e-seer | Kitaab - Al - U'mdah - fil - Jeraahat, Part II | Aminuddaulah Abul Farj Ibn Al-Quff Maseehi, Dayerah-al- Ma'aarif Usmania, Hyderabad, 1937 | Unani |
Information from Wealth of India | Reference |
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CSIR(1948).The Wealth of India, Raw materials,Vol.-I ,P.58-59, New Delhi, India |
4.2, 04.2.1, 04.2.1.1, 04.2.1.3, 04.2.2.3, 04.2.2.5, 04.2.2.6, 04.2.2.8 |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |