Vaccinium oxycoccos
Cranberries are red coloured small berries, evergreen in nature and are native to North America. The plant is a trailing dwarf shrub and are found in temperate climatic conditions, now are available in almost all parts of the world. The fruits are small berries but are larger than the leaves of the plant, green in colour and tends to turn red or dark pink when ripe, tastes slightly bitter acidic and sweet. It is eaten raw or dried, used to prepare juices and jellies. In many countries, cranberries are considered as a super food due to its antioxidant potential. Besides, Cranberries are a good source of vitamins, bioactive compounds that helps to enhance the immune system. Many sources have reported that, cranberries are used as a treatment to UTIs and kidney diseases in many traditional practices. And besides this, the metabolites or bioactive compounds reported to be found in the fruit also helps to suppress the NF-kB pathway and impedes the activity of cyclooxygenases and lipooxygenases initiating an anti-inflammatory response in the body. |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Vaccinium oxycoccos L. Family: Ericaceae Durande Class: Magnoliopsida Order: Ericales Genus: Vaccinium L. Fruiting Season: April to November Fruting Condition: Unripe |
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Ripe fruits on display. Ripe fruits in red colour with plants. Ripe fruits in red colour with plants. |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Fruit extract | Anti-inflammatory activity | Fruit extract exhibited a powerful suppressor to the nuclear factor (NF)-ĸB-pathway. It also impedes the activities of cyclooxygenase and lipoxygenase, enzymes released after the stimulation of arachidonic acid, which is the initiator of an inflammatory response. It also has been shown to reduce inflammatory genes expression important for cardiovascular disease by regulating the NF-ĸB and JAK STAT3 pathways in cells. | NF-ĸB, JAK-STAT3,[2] |
Fruit extract | Anti-inflammatory activity | It also improved post-prandial glucose concentration due to high fat and inflammation and oxidation in diabetic individuals. | [2] |
Major Class | Metabolites |
Anthocyanin | Delfinidyn-3-O-glucoside(Whole fruit), Cyanidin-3-O-galactoside(Whole fruit), Cyanidin-3-O-glucoside(Whole fruit), Cyanidin-3-O-arabinoside(Whole fruit), Peonidin-3-O-galactoside(Whole fruit), Peonidin-3-O-arabinoside(Whole fruit), Malvidin-3-O-arabinoside(Whole fruit) |
Flavonoid | Myricetin-3-O-galactoside(Whole fruit), Myricetin-3-O-glucoside(Whole fruit), Myricetin-3-O-pentoside(Whole fruit), Myricetin-3-Oglucoronide(Whole fruit), Quercetin-3-O-galactoside(Whole fruit), Quercetin-3-O-pentoside(Whole fruit), Quercetin-3-O-glucoside(Whole fruit), Quercetin-3-Orhamnoside(Whole fruit), Methoxyquercetin hexoside(Whole fruit), Methoxyquercetin pentoside(Whole fruit), (+)-catechin(Whole fruit), (−)-epicatechin(Whole fruit) |
Phenolic acid | p-coumaric acid(Whole fruit), Chlorogenic acid(Whole fruit), Caffeic acid(Whole fruit), Ferulic acid(Whole fruit) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
NA | NA | Fruit | Positive effect of on liver enzymes and cardiometabolic risk factors in patients with non alcoholic fatty liver disease[5] |
04.1.2.12, 04.1.2.5 |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |