Rubus ellipticus
Rubus ellipticus also known as ainselu or golden himalayan raspberry is native to India,Pakistan, Nepal and China. It is a species of thorny fruiting shrub in the rose family. It is not commonly harvested for domestic use.The berries contains secondary metabolites like gallic acid and catechin which are repoted to have antiproliferative and inflammatory |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Rubus ellipticus Sm. Family: Rosaceae Sm. Class: Magnoliopsida Order: Rosales Genus: Rubus Sm. Fruiting Season: August and september Fruting Condition: Ripe |
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Assam : Bor-jetuli-poka, Borjetulipoka, Joteli-poka, Jotelupoka Gujarat : Shunu Mukram Jammu and Kashmir : Gouriphal, Hisara Kerala : Cheemullu, Mullippazham Ladakh : ainselu, ainselu Manipur : Heijampet |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Gallic acid | Anti-inflammatory activity | Gallic acid inhibits the activities of NF-κB and MAPK, subsequently inhibiting the release of inflammatory factors (TNF-α, IL-1β/6), chemokines (CCL-2, ICAM-1, TIMP-1) and other inflammatory mediators such as COX-2 and NO.It also decreases inflammatory cell infiltration, thereby ameliorating the the inflammatory response | [1] |
Catechin | Anti-inflammatory activity | Catechin mediates ferroptosis to exert an Anti-inflammatory activity effect on RAW 264.7 cells | [3][7] |
Caffeic acid | Antiproliferative activity | Caffeic acid demonstrates activity against HCC, preventing the exaggerated formation of ROS and assisting in the killing of tumor cells through DNA oxidationas well as angioneogenesis by acting to reduce VEGF-induced vascularisation and suppression of MMP-2 and MMP expression−9. | [2] |
Major Class | Metabolites |
Flavonoid | Catechin(Pulp), Catechin(Pulp) |
Phenolic acid | Gallic acid(Pulp), Caffeic acid(Pulp), Gallic acid(Pulp), Caffeic acid(Pulp) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
04.1.1, 04.1.1 |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |