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Pyrus communis

Commonly known as Pear or Nashpati is grown in the sates of Punjab, Himachal pradesh, JK UT and Uttarakhand in large scale. It belongs to the family rosaceae and ot is generally harvested in the months of May and June. Pear peel contains a glycosylated hydroquinone known as Arutin which has been reported to have many biological property including antiproliferative activity and free radical scavenging activity.Arbutin can exert anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascade and also can suppress osteosarcoma progression via miR-338-3p/MTHFD1L and inactivation of the AKT/mTOR pathway.

Mode of Consumption: Mostly consumed Raw, Used to prepare Juice, Jam, Pickles Dried fruits etc

Plant Details Agro-climatic Zone Vernacular Names Pictures
Scientific Name: Pyrus communis L.
Family: Rosaceae L.
Class: Magnoliopsida
Order: Rosales
Genus: Pyrus L.
Fruiting Season: May – June and July – October
Fruting Condition: Ripe
  • North-Western Mountain Region
  • Southern plateau and Hills Region & West Coast Plains and Ghat Region
  • West Coast Plains and Ghat Region & East Coast Plains and Hills Region

Himachal pradesh : naashapaatee, naashapaatee
Karnataka : Marasebu
Tamil Nadu : Pērikkāy, Pērikkāy
Compound/Chemical Immunomodulatory Activity Pathway Immunomodulatory Marker
ArbutinAntiproliferative activityArbutin can exert anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascadep13[3][4]
ArbutinAntiproliferative activityArbutin can suppress osteosarcoma progression via miR-338-3p/MTHFD1L and inactivation of the AKT/mTOR pathway[3][4]
Chlorogenic acidAntioxidant activityFree radical scavenging and protects against oxidative stress[2][5][9]
Syringic acidAntiproliferative activitySyringic acid acts as an anti-cancer agent by reducing cellular proliferation, inducing apoptosis, alteration of autophagy through modulating oxidative stress and key proteins involved in cellular proliferation[1][8]
Major Class Metabolites
Gycosylated hydroquinone Arbutin(Peel), Arbutin(Peel)
Phenolic acidChlorogenic acid(Pulp), Syringic acid(Pulp), Chlorogenic acid(Pulp), Syringic acid(Pulp)
Traditional Practice Diseases Plant Part Additional Knowledge
FruitReduced inflammatory factors and oxidative stress in patients with type 2 diabetes mellitus[10]
04.1.1, 04.1.1
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India