Prunus salicina
Plums also known as aloobhukhara belongs to the family rosaceae. Plums are largely grown in staes of Uttarakhand and Himachal pradesh together they make up 65% of plum production in India.It harvested in the months of Apirl and May. Plums are rich phytochemicals such as anthocyanins and phenolic acid which are beneficial to human health. Neo chlogenic acid one of the major compund of plums has been shown to have anti-inflammatory activity by inhibiting against LPS-activated inflammatory responses through up-regulation of Nrf2/HO-1 and involving AMPK pathway. Cyanidin-3-O-glucoside belonging to anthocyanins are shown have anti-inflammatory in nature. |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Prunus salicina Lindl. Family: Rosaceae L. Class: Magnoliopsida Order: Rosales Genus: Prunus L. Fruiting Season: Apirl - May Fruting Condition: Ripe |
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Himachal pradesh : Palam, aaloobukhaara, aaloobukhaara |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Neochlorogenic acid | Anti-inflammatory activity | Neochlorogenic acid inhibits against LPS-activated inflammatory responses through up-regulation of Nrf2/HO-1 and involving AMPK pathway | [6][7][9] |
Neochlorogenic acid | Anti-inflammatory activity | Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells | [6][7][9] |
Rosmarinic acid | Antiproliferative activity | Rosmarinic Acid Activates AMPK to Inhibit Metastasis of Colorectal Cancer | [2][4] |
Cyanidin-3-O-glucoside | Anti-inflammatory activity | Cyanidin-3-O-Glucoside Ameliorates LipopolysaccharideInduced Injury Both In Vivo and In Vitro Suppression of NF-κB and MAPK Pathways | [1][3][5] |
Cyanidin-3-O-glucoside | Anti-inflammatory activity | Cyanidin-3-O-glucoside counters the response to TNF-alpha of endothelial cells by activating Nrf2 pathway | [1][3][5] |
Major Class | Metabolites |
Anthocyanins | Cyanidin-3-O-glucoside(Pulp) |
Phenolic acid | Neochlorogenic acid(Pulp), Neochlorogenic acid(Pulp), Rosmarinic acid(Pulp) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
Fruit | Reduced blood markers of bone turnover, and inflammation in breast cancer survivors[10] |
04.1.1, 04.1.2 |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |