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Prunus persica var. nucipersica

Summary

Nectarines are subspecies of peaches (Prunus persica).They are reddish in colour with fuzzy hair like structure on the peel. Nectarines are grown in Hiamcahl pradesh and uttrakhand and are harvested in the month of March and May. These fruits contain high concentration of chlorogenic acid and neo chlorogenic acid which has potential to act as chemopreventive dietary compound because of the relatively high growth inhibition exerted on the estrogen-independent MDA-MB-435 breast cancer cell line and low toxicity exerted in the normal MCF-10A cells Mode of Consumption: Mostly consumed Raw, Used to prepare Juice, Jam, Pickles Dried fruits etc

Plant Details and Distribution

Plant Details	Agro-climatic Zone	Vernacular Names	Pictures
Scientific Name: Prunus persica var. nucipersica (L.) Borkh. Family: Rosaceae L. Class: Magnoliopsida Order: Rosales Genus: Prunus L. Fruiting Season: March -May Fruting Condition: Ripe	North-Western Mountain Region	Himachal pradesh : Nectarine, Shaftalu

Immunomodulatory Activity

Compound/Chemical	Immunomodulatory Activity	Pathway	Immunomodulatory Marker
Neochlorogenic acid	Antiproliferative activity	Neo-chlorogenic acids has the potential to act as chemopreventive dietary compound because of the relatively high growth inhibition exerted on the estrogen-independent MDA-MB-435 breast cancer cell line and low toxicity exerted in the normal MCF-10A cells	^[5]
Vanillic acid	Antiproliferative activity	Vanillic Acid Suppresses HIF-1α Expression via Inhibition of mTOR/p70S6K/4E-BP1 and Raf/MEK/ERK Pathways in Human Colon Cancer HCT116 Cells and it can also inhibit inflammatory mediators by suppressing NF-κB in lipopolysaccharide-stimulated mouse peritoneal macrophages	NF-κB^[2][12]
Syringic acid	Antiproliferative activity	Syringic acid prevents skin carcinogenesis via regulation of NoX and EGFR signaling	^[3]

Metabolites

Major Class	Metabolites
Phenolic acid	Neochlorogenic acid(Pulp), Vanillic acid(Pulp), Syringic acid(Pulp)

Epidemiological Data

Traditional Practice	Diseases	Plant Part	Additional Knowledge

FSSAI Category

04.1.1

Forbidden Combination

NA

References

References 1 . DOI: 10.3390/molecules26092818 2 . DOI: 10.3109/08923973.2010.547500 3 . DOI: 10.1016/j.bcp.2018.06.007 4 . DOI: 10.1111/jfpp.15198 5 . DOI: 10.1016/j.jfca.2020.103502 6 . DOI: 10.1051/fruits/2015042 7 . DOI: 10.1021/jf0104681 8 . DOI: 10.1055/a-0955-5876 9 . DOI: 10.3390/foods11071010 10 . DOI: 10.1021/jf900259m 11 . DOI: 10.3390/ijms20030465

CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India