Myrica esculenta
Also known as Kaphal/box myrtle,/bayberry is an underutilized fruit predominently found in Uttarakhand and Himachal pradesh. It belongs to the family Myricaceae and is harvested in the months of April and May. These berries are consumed locally and cannot be found other major staes of India. Kaphal berries have been reported to have anti-inflammmatory actvity, it can inhibit the activation of inflammatory factors such as HIF-1a, ICAM-1, VCAM-1, TNF-α, IL-6, and nuclear factor-kappa B (NK-κB) p65, thus protecting cerebral ischemia/reperfusion injury |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Myrica esculenta Buch.-Ham. Family: Myricaceae L. Class: Magnoliopsida Order: Fagales Genus: Myrica L. Fruiting Season: Apirl - May Fruting Condition: Ripe |
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Himachal pradesh : Kaphal, Kaphal Uttarakhand : Kaphal, Kaphal |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Chlorogenic acid | Anti-inflammatory activity | Chlorogenic acid has a strong antiinflammatory effect on arachidonic acid metabolism by inhibiting the activation of inflammatory factors such as HIF-1a, ICAM-1, VCAM-1, TNF-α, IL-6, and nuclear factor-kappa B (NK-κB) p65, thus protecting cerebral ischemia/reperfusion injury | HIF-1a, ICAM-1, VCAM-1, TNF-α, IL-6[2][1] |
P-coumaric acid | Antiproliferative activity | p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer | NA[3][2] |
Major Class | Metabolites |
Phenolic acid | Chlorogenic acid(Pulp), P-coumaric acid(Pulp), Chlorogenic acid(Pulp), P-coumaric acid(Pulp) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
04.1.1, 04.1.1 |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |