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Garcinia morella

Summary

Garcinia morella known as Indian gamboges. It was a fruit-yielding tree belonging to the family Clusiaceae and also a close relative of mangosteen (G. mangostana). In India, it is commonly distributed in the Western Ghats and north-eastern regions. Fruits are berries with a diameter of 3 cm that contain four seeds. Several secondary metabolites have been isolated from the fruits and seeds of Indian gamboge. The major isolated phytochemicals were xanthones, benzophenones, flavonoids, phenolic acid, triterpenoids, and fatty acids. Isolated compound garcinol showed potent anti-oxidant activity against MCF7, MDAMB231, and SKBR3 cell lines

Mode of Consumption: Mostly consumed Raw, Used to prepare Juice, Jam, Pickles Dried fruits etc
Plant Details Agro-climatic Zone Vernacular Names Pictures
Scientific Name: Garcinia morella Gaertn.
Family: Clusiaceae Desr.
Class: Dicotyledons
Order: Malpighiales
Genus: Garcinia L.
Fruiting Season: May to June
Fruting Condition: Ripe
  • Eastern Himalayan Region
  • West Coast Plains and Ghat Region & East Coast Plains and Hills Region

 Assam : Kuji thekera
Mizoram : Kawr-vawmva
Tamil Nadu : Iravasinni, makki
Compound/Chemical Immunomodulatory Activity Pathway Immunomodulatory Marker
Fuit extractsAnti-oxidant activityMethanol and chloroform extract of fruits were showed potential anti-oxidant activity against in MCF7, MDAMB231, and SKBR3 cell linesNO inhibits[1][2]
Fuit extractsAnti-oxidant activityWater extract of fruits also exhibited potentia rule of anti-oxidant activityNO inhibits[1][2]
GarcinolAnti-oxidant activityIsolated compound garcinol showed potent anti-oxidant activity against in MCF7, MDAMB231, and SKBR3 cell linesNO, TNF-alpha[1][2]
Fuit extractsAnti-inflamatory activityChloroform extract of fruits were revealed that it significantly lowered the release of nitrite and TNF-α level of LPS induced RAW 264.7 cells (p < 0.05).NO, TNF-alpha[1][2]
Major Class Metabolites
Benzopyran derivativesDihydroisomorellin(Whole fruit), Desoxymorellin(Whole fruit), Moreollin(Whole fruit), Morellin(Whole fruit), Isomorellin(Whole fruit)
Carboxylic acid derivativesMorellic acid(Whole fruit)
Traditional Practice Diseases Plant Part Additional Knowledge
AyurvedaOedema / Inflammation, Anaemia / HyperbilirubinaemiaPlant isolatePhase IIa study for advanced cancer treatment by gambogic acid injection [3]
04.1.1.3
Incompatible with Milk, Curd and cheese
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India