Ficus carica
Figs are nutritious fruits distributed in many regions of India and other countries, belonging to the Moraceae family. the fruits are known to be rich in nutrients such as potassium, calcium, vitamins and dietary fibers etc. Additionally, they are an excellent source of minerals and bioactive compounds which exhibits antioxidant properties. Compounds such as Vitamin C, Tocopherols, carotenoids and phenolic acids present in the fruit are reported to inhibit the ROS production in the cells. On the other hand, it is also reported to exhibit anti-hyperglycemic and anti-inflammatory activities. The consumption of this fruit in a periodic manner helps to inhibit the activities of the enzymes such as alpha-amylase, alpha-glucosidase and pancreatic lipase in the body. The fruit also has potential to exhibit anti-inflammatory activities such as in inducing the cytokine production (IL-6 and TNF-alpha) in the cells and helping to induce lymphocyte proliferation in the body. |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Ficus carica L. Family: Moraceae Gaudich. Class: Magnoliopsida Order: Rosales Genus: Ficus Tourn. ex L. Fruiting Season: May to June Fruting Condition: Ripe |
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Unripe fruits on tree. Ripe fruits on tree. Single ripe fruit on tree. |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Antioxidant acitvity | Fruit extract inhibited the chemiluminescence of lucigenin and ROS production and differed from each other according to the concentration of the sample and the incubation time. | ROS[3] | |
Fruit extract | Antihyperglycemic activity | It inhibited the activities of the enzymes α-amylase, α-glucosidase, and pancreatic lipase. It reduce the digestion and absorption of carbohydrates and lipids and also to reduce significantly the blood glucose and body fat levels. | Alpha amylase and glucosidase inhbitions[1] |
Fruit extract | Anti-inflammatory activity | The test drugs of the fruit extract was seen to induce cytokine production (including IL-6 and TNF- alpha) and also induces lymphocyte proliferation in a dose dependent manner. | IL-6, TNF-alpha[3] |
Major Class | Metabolites |
- | 4,6-O-benzylidene-D-glucose(Whole fruit), 24-methylenecycloartano(Whole fruit), 4-methylpyridine(Whole fruit), Acetaldehyde(Whole fruit), Acetic acid(Whole fruit), Alpha-bourbonene(Whole fruit), Epoxylinalool(Whole fruit), Terpinolene(Whole fruit), Alpha-caryophyllene(Whole fruit), Betulol(Whole fruit), Biochanin A(Whole fruit), Cyanidin-3-rhamnoglucoside (C3R)(Whole fruit) |
Acyloins | Acetoin(Whole fruit) |
Amino acid | DL-alanine-15N(Whole fruit) |
Carboxylic acid esters | Calotropenyl acetate(Whole fruit), 2-methylbutyle acetate(Whole fruit) |
Coumarin | Bergapten(Whole fruit), Nodakenetin(Whole fruit), Psoralen(Whole fruit) |
Flavonoid | Quercetin(Whole fruit), Quercetin-3-O-glucoside(Whole fruit), Quercetin-3-O-rutinoside(Whole fruit) |
Glycoside | Oleanolic acid(Whole fruit) |
Phenolic acid | 3-O-caffeoylquinic acid(Whole fruit), 5-O-caffeoylquinic acid(Whole fruit), Quinin acid(Whole fruit) |
Sterol | Taraxasterol(Whole fruit), Lupeol(Whole fruit), Beta-sisterol(Whole fruit), Lanosterol(Whole fruit), Lupeol acetate(Whole fruit), 6-O-acyl-beta-D-glucosyl-beta-sitoSterol(Whole fruit) |
Terpenoid | Limonene(Whole fruit), Germacrene D(Whole fruit), Cadinene(Whole fruit), Luteolin(Whole fruit), Alpha-guaiene(Whole fruit), Alpha-calacorene(Whole fruit) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
04.1.2.12 |
Incompatible with Milk and Yogurt |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |