Citrus × sinesis
| Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
| Scientific Name: Family: Class: Order: Genus: Fruiting Season: Fruting Condition: |
|
Himachal Pradesh : Santara Karnataka : Kittaḷe Tamil Nadu : Ārañcu |
| Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
| Naringin | Antiproliferative activity | Inhibit enzymes involved in cell activation. | NA[1][2] |
| Tangeretin | Antiproliferative | Antiproliferative action against antigen activated T-lymphocytes. | NA[1] |
| Nobiletin | Antiproliferative | Antiproliferative action against antigen activated T-lymphocytes. | NA[1] |
| Hesperidine | Antioxidant activity | Donates hydrogen ions to free radicals and neutralise their harmful effect. | NA[1] |
| Nobiletin | Anti-inflammatory activity | Inhibition of COX-1, COX-2, LOX,NF-κB, TNF, ILs, LTs | NF-κB, TN[1] |
| Tangereti | Anti-inflammatory activity | Inhibits enzymes that regulate the biosynthesis of pro-inflammatory mediators which are responsible for activation of cells that cause inflammation. | NA[1] |
| Vitamin C | Antioxidant activity | Inhibits generation of free radicles. | NA[1][4] |
| Vitamin A | Antioxidant activity | Potentiate antibody responses to T cell dependent antigens, increase lymphocyte proliferation and inhibit apoptosis. | NA[1][4] |
| Beta carotene | Antioxidant activity | Responsible for secretion of immunomodulatory lipid molecules like leukotriens and Prostaglandins. | NA[1] |
| Folic acid | Antioxidant activity | Supports proliferation of Treg cells. | NA[1] |
| Major Class | Metabolites |
| Traditional Practice | Diseases | Plant Part | Additional Knowledge |
| CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |