Carica papaya
In India, papaya is predominantly grown in Tamil Nadu, Karnataka, Andhra Pradesh, and Gujarat. India is the largest producer of papaya in the world with 6 million tonnes in 2020. It is harvested between August and November. Papaya belongs to Caricaceae family and it contains alkaloids, Carotenoids, phenolics and flavonoids. Lycopene, quercetin, kaempferol, and vitamin C are some of the most important bioactive chemicals. Lycopene has been shown to have anti-oxidant action by scavenging free radicals, as well as anticarcinogenic activity by regulating the cell cycle and suppressing aberrant cell development. Quercetin has anti-inflammatory properties via suppressing IL-6 and IL-8. Vitamin C scavenges ROS generated by cellular metabolism. |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Carica papaya L. Family: Caricaceae Dumort. Class: Mangoliopsida Order: Brassicales Genus: Carica L. Fruiting Season: August-November Fruting Condition: Ripe |
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Himachal Pradesh : Papita, Papita Karnataka : Papayi, Papayi Tamil Nadu : Pappāḷi, Pappāḷi |
Unripe fruit hanging from the tree. Ripe Papaya cut into halves. |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Vitamin C, Gallic acid, Ellagic acid, Quercetin | Anti-inflammatory activity | Enhance Proliferation of T lymphocytes & increase the synthesis of IgG & cytokinin production. | Cytokines[1] |
Vitamin A, Gallic acid, Ellagic acid, Quercetin | Anti-inflammatory activity | Enhance white blood function, enhance resistance to infection and maintain skin and mucous membrane defences. | NA[1] |
Lycopene | Antioxidant activity | Free radical scavenger | NA[2] |
Vitamin A, Gallic acid, Ellagic acid, Quercetin | Antioxidant activity | Neutralise the harmful effects of free radicals. | NA[1] |
Vitamin C, Gallic acid, Ellagic acid, Quercetin | Antioxidant activity | Scavanges ROS produces due to cellular metabolism. | NA[1] |
Quercetin | Antioxidant activity | Suppress IL-6 & IL-8 | IL-6 & IL-8[1] |
Major Class | Metabolites |
Carotenoid | Lycopene(Pulp) |
Cysteine protease | Papain(Pulp) |
Flavonoid | Quercetin(Pulp), Kaempherol(Pulp) |
Organic compounds | Choline(Pulp) |
Vitamins | Vitamin A(Pulp), Vitamin C(Pulp) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
Leaves | Dengue fever treatment with Carica papaya leaves extracts[3] |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |