Aegle marmelos
Bael is a fruit of the Rutaceae family, and is widely famous for its high nutrient value, traditional medicinal usage and many other pharmacological properties. The pulp of the fruit comprises of fibers, carotenoids, phenolic acids, terpenoids, flavonoids and alkaloids. Marmelin is a bioactive compound which has anti-inflammatory potential by helping in the reduction of Interleukin-8 marker in the body. Besides, the fruit has very high anti-inflammatory activity potential by effecting the bio markers IL-4, TNF-alpha and IL-6. |
Plant Details | Agro-climatic Zone | Vernacular Names | Pictures |
Scientific Name: Aegle marmelos (L.) Correa Family: Rutaceae Juss. Juss. Class: Magnoliopsida Order: Sapindales Genus: Aegle Corrêa Fruiting Season: February-April Fruting Condition: Ripe |
|
Andhra Pradesh : Maredu Assam : Bael Gujarat : Bili , Bilivaohal Himachal Pradesh : Bil Karnataka : Bilvapatre Kerala : Koolakam, Kuvalum Maharashtra : Bel Odisha : Belo Tamil Nadu : Bilva Pandu, Vilva marum Uttar Pradesh : Bael West Bengal : Bael |
Whole ripe fruit. Tree with fruitts. Whole plant. |
Compound/Chemical | Immunomodulatory Activity | Pathway | Immunomodulatory Marker |
Marmelin | Anti-inflammatory activity | Marmelin in the fruit extract of the fruit helps in the reduction of IL-8. | IL-8[9] |
Ethanolic extract | Anti-inflammatory activity | The ethanolic extract of the fruit was seen to significantly show reduction in TNF-alpha serum biomarker, Makondialdehyde (MDA) levels and glucose levels. | TNF-alpha, MDA[7] |
Fruit extract | Anti-inflammatory activity | The fruit extract in in vivo analysis showed that it helps to decrease monoamine oxidase-A (MAO-A) activity and IL-6 level. | IL-6, MAO-A[4][8] |
LI3109F herbal formulation | Anti-inflammatory activity | The herbal formulation LI3109F increases in serum IFN-gamma and reduces IL-4, infiltrated granulocyte population in the bronco-alveolar lavage fluid and normalized Th1/Th2 cytokine balance. | IL-4, IFN-gamma[5] |
Major Class | Metabolites |
- | Marmelide(Fruit) |
Alkaloid | Marmesiline (Fruit), Shahidine(Fruit) |
Carotenoid | Alpha-carotene(Fruit), Beta-carotene(Fruit), Gamma-carotene(Fruit), Delta-carotene(Fruit) |
Coumarin | Luvangetin(Fruit), Aurapten(Fruit), Psoralen(Fruit) |
Flavonoid | Rutin (Fruit), Kaempferol (Fruit), Quercetin(Fruit) |
Phenolic acid | Gallic acid(Fruit), 2,3-dihydroxy benzoic acid(Fruit), Chlorogenic acid(Fruit), p-coumaric acid(Fruit), vanillic acid(Fruit) |
Tannin | Tannin(Fruit) |
Traditional Practice | Diseases | Plant Part | Additional Knowledge |
Siddha | Vomiting ,Polydipsia | Leaf | Control type 2 diabetes mellitus and oxidative stress[10] |
4.1, 04.1.1, 04.1.1.1, 04.1.2.8 |
Incompatible with Milk and Yogurt |
CSIR-North East Institute of Science and Technology, Jorhat-6, Assam, India
CSIR-Institute of Himalayan Bioresource Technology, Palampur-61,Himachal Pradesh, India |