OSADHI - Online Structural and Analytics based Database for Herbs of India

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Chemoinformaics analysis of Uridine


Physiochemical Properties
Molecular Weight 244.203 nRot 2
Heavy Atom Molecular Weight 232.107 nRig 13
Exact Molecular Weight 244.07 nRing 2
Solubility: LogS -0.933 nHRing 2
Solubility: LogP -1.968 No. of Aliphatic Rings 1
Acid Count 0 No. of Aromatic Rings 1
Base Count 0 No. of Aliphatic Carbocycles Rings 0
Atoms Count 29 No. of Aliphatic Hetero Cycles 1
No. of Heavy Atom 17 No. of Aromatic Carbocycles 0
nHetero 8 No. of Aromatic Hetero Cycles 1
nBridge Head 0 No. Saturated Carbocycles 0
No. of Hydrogen atom 12 No. of Saturated Hetero Cycles 1
No. of Carbon atom 9 No. of Saturated Rings 1
No. of Nitrogen atom 2 No. of Arom Atom 6
No. of Oxygen atom 6 No. of Arom Bond 6
nHA 7 APOL 30.0435
nHD 4 BPOL 17.7905
Medicinal Chemistry Properties
QED 0.444
Synth 3.484
Natural Product Likeliness 1.49
NR-PPAR-gamma 0.003
Drug Likeliness
Lipinski Accepted
Pfizer Accepted
GSK Accepted
Golden Triangle Accepted
Absorption
Pgp-inh 0
Pgp-sub 0.015
HIA 0.944
CACO-2 -6.001
Distribution
MDCK 0.00186046
BBB 0.844
PPB 0.12732
VDSS 0.308
Metabolism
FU 0.776439
CYP1A2-inh 0.005
CYP1A2-sub 0.102
CYP2c19-inh 0.018
CYP2c19-sub 0.048
CYP2c9-inh 0.001
CYP2c9-sub 0.092
CYP2d6-inh 0.007
CYP2d6-sub 0.101
CYP3a4-inh 0.004
CYP3a4-sub 0.02
Excretion
CL 5.065
T12 0.8
Toxicity
hERG 0.005
Ames 0.039
ROA 0.022
SkinSen 0.035
Carcinogencity 0.028
EI 0.009
Respiratory 0.023
NR-Aromatase 0.006
Antiviral Prediction
Antiviral No
Prediction 0.815258
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A database of all the medicinal plants having PAN India presence.
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