Chemoinformaics analysis of Dillenetin
Molecular Weight | 330.292 | nRot | 3 |
Heavy Atom Molecular Weight | 316.18 | nRig | 18 |
Exact Molecular Weight | 330.074 | nRing | 3 |
Solubility: LogS | -3.667 | nHRing | 1 |
Solubility: LogP | 2.858 | No. of Aliphatic Rings | 0 |
Acid Count | 0 | No. of Aromatic Rings | 3 |
Base Count | 0 | No. of Aliphatic Carbocycles Rings | 0 |
Atoms Count | 38 | No. of Aliphatic Hetero Cycles | 0 |
No. of Heavy Atom | 24 | No. of Aromatic Carbocycles | 2 |
nHetero | 7 | No. of Aromatic Hetero Cycles | 1 |
nBridge Head | 0 | No. Saturated Carbocycles | 0 |
No. of Hydrogen atom | 14 | No. of Saturated Hetero Cycles | 0 |
No. of Carbon atom | 17 | No. of Saturated Rings | 0 |
No. of Nitrogen atom | 0 | No. of Arom Atom | 16 |
No. of Oxygen atom | 7 | No. of Arom Bond | 17 |
nHA | 7 | APOL | 43.3391 |
nHD | 3 | BPOL | 20.1209 |
QED | 0.677 |
Synth | 2.337 |
Natural Product Likeliness | 1.307 |
NR-PPAR-gamma | 0.953 |
Lipinski | Accepted |
Pfizer | Accepted |
GSK | Accepted |
Golden Triangle | Accepted |
Pgp-inh | 0.312 |
Pgp-sub | 0.028 |
HIA | 0.031 |
CACO-2 | -4.938 |
MDCK | 0.0000125 |
BBB | 0.005 |
PPB | 0.939528 |
VDSS | 0.806 |
FU | 0.101635 |
CYP1A2-inh | 0.949 |
CYP1A2-sub | 0.936 |
CYP2c19-inh | 0.254 |
CYP2c19-sub | 0.059 |
CYP2c9-inh | 0.679 |
CYP2c9-sub | 0.878 |
CYP2d6-inh | 0.596 |
CYP2d6-sub | 0.631 |
CYP3a4-inh | 0.624 |
CYP3a4-sub | 0.137 |
CL | 6.421 |
T12 | 0.912 |
hERG | 0.05 |
Ames | 0.567 |
ROA | 0.069 |
SkinSen | 0.457 |
Carcinogencity | 0.033 |
EI | 0.705 |
Respiratory | 0.195 |
NR-Aromatase | 0.887 |
Antiviral | Yes |
Prediction | 0.859939 |