Chemoinformaics analysis of Aciphyllyl alcohol
Molecular Weight | 220.356 | nRot | 2 |
Heavy Atom Molecular Weight | 196.164 | nRig | 12 |
Exact Molecular Weight | 220.183 | nRing | 2 |
Solubility: LogS | -4.176 | nHRing | 0 |
Solubility: LogP | 3.962 | No. of Aliphatic Rings | 2 |
Acid Count | 0 | No. of Aromatic Rings | 0 |
Base Count | 0 | No. of Aliphatic Carbocycles Rings | 2 |
Atoms Count | 40 | No. of Aliphatic Hetero Cycles | 0 |
No. of Heavy Atom | 16 | No. of Aromatic Carbocycles | 0 |
nHetero | 1 | No. of Aromatic Hetero Cycles | 0 |
nBridge Head | 0 | No. Saturated Carbocycles | 1 |
No. of Hydrogen atom | 24 | No. of Saturated Hetero Cycles | 0 |
No. of Carbon atom | 15 | No. of Saturated Rings | 1 |
No. of Nitrogen atom | 0 | No. of Arom Atom | 0 |
No. of Oxygen atom | 1 | No. of Arom Bond | 0 |
nHA | 1 | APOL | 41.855 |
nHD | 1 | BPOL | 24.077 |
QED | 0.704 |
Synth | 4.122 |
Natural Product Likeliness | 2.626 |
NR-PPAR-gamma | 0.004 |
Lipinski | Accepted |
Pfizer | Rejected |
GSK | Accepted |
Golden Triangle | Accepted |
Pgp-inh | 0.016 |
Pgp-sub | 0 |
HIA | 0.004 |
CACO-2 | -4.514 |
MDCK | 0.0000111 |
BBB | 0.981 |
PPB | 0.913542 |
VDSS | 2.375 |
FU | 0.036766 |
CYP1A2-inh | 0.262 |
CYP1A2-sub | 0.472 |
CYP2c19-inh | 0.042 |
CYP2c19-sub | 0.605 |
CYP2c9-inh | 0.058 |
CYP2c9-sub | 0.332 |
CYP2d6-inh | 0.006 |
CYP2d6-sub | 0.77 |
CYP3a4-inh | 0.121 |
CYP3a4-sub | 0.4 |
CL | 11.08 |
T12 | 0.171 |
hERG | 0.013 |
Ames | 0.073 |
ROA | 0.032 |
SkinSen | 0.299 |
Carcinogencity | 0.788 |
EI | 0.525 |
Respiratory | 0.583 |
NR-Aromatase | 0.007 |
Antiviral | Yes |
Prediction | 0.917645 |